Absence of detectable measles virus genome sequence in inflammatory bowel disease tissues and peripheral blood lymphocytes

1998 ◽  
Vol 55 (3) ◽  
pp. 243-249 ◽  
Author(s):  
M. A. Afzal ◽  
E. Armitage ◽  
J. Begley ◽  
M. L. Bentley ◽  
P. D. Minor ◽  
...  
Keyword(s):  
Inflammatory Bowel Disease ◽  
Genome Sequence ◽  
Bowel Disease ◽  
Peripheral Blood ◽  
Measles Virus ◽  
Virus Genome ◽  
Peripheral Blood Lymphocytes ◽  
Blood Lymphocytes ◽  
Inflammatory Bowel

scholarly journals Immunophenotype of Peripheral Blood Lymphocytes in Dogs with Inflammatory Bowel Disease

2017 ◽  
Vol 31 (6) ◽  
pp. 1730-1739 ◽  
Author(s):  
A. Galler ◽  
B.C. Rütgen ◽  
E. Haas ◽  
A. Saalmüller ◽  
R.A. Hirt ◽  
...  
Keyword(s):  
Inflammatory Bowel Disease ◽  
Bowel Disease ◽  
Peripheral Blood ◽  
Peripheral Blood Lymphocytes ◽  
Blood Lymphocytes ◽  
Inflammatory Bowel

Absence of measles-virus genome in inflammatory bowel disease

The Lancet ◽  
1998 ◽  
Vol 351 (9103) ◽  
pp. 646-647 ◽  
Author(s):  
MA Afzal ◽  
PD Minor ◽  
J Begley ◽  
ML Bentley ◽  
E Armitage ◽  
...  
Keyword(s):  
Inflammatory Bowel Disease ◽  
Bowel Disease ◽  
Measles Virus ◽  
Virus Genome ◽  
Inflammatory Bowel

scholarly journals FOXP3+T Regulatory Cell Modifications in Inflammatory Bowel Disease Patients Treated with Anti-TNFαAgents

2013 ◽  
Vol 2013 ◽  
pp. 1-10 ◽  
Author(s):  
Luisa Guidi ◽  
Carla Felice ◽  
Annabella Procoli ◽  
Giuseppina Bonanno ◽  
Enrica Martinelli ◽  
...  
Keyword(s):  
Rheumatoid Arthritis ◽  
Inflammatory Bowel Disease ◽  
Flow Cytometry ◽  
Bowel Disease ◽  
Peripheral Blood ◽  
Disease Duration ◽  
Healthy Controls ◽  
T Regulatory Cell ◽  
Inflammatory Bowel ◽  
Necrosis Factor

Treg modulation has been hypothesized as one of the mechanisms by which antitumor necrosis factorα(TNFα) agents exert their action in rheumatoid arthritis (RA) and inflammatory bowel disease (IBD). However, data in IBD are still conflicting. We evaluated CD4+CD25+FOXP3+(Tregs) by flow cytometry in peripheral blood from 32 adult IBD patient before (T0) and after the induction of anti-TNFαtherapy (T1). Eight healthy controls (HCs) were included. We also evaluated the number of FOXP3+cells in the lamina propria (LP) in biopsies taken in a subset of patients and controls. Treg frequencies were significantly increased in peripheral blood from our patients after anti-TNFαtherapy compared to T0. T1 but not T0 levels were higher than HC. The increase was detectable only in clinical responders to the treatment. A negative correlation was found among delta Treg levels and the age of patients or disease duration and with the activity score of Crohn’s disease (CD). No significant differences were found in LP FOXP3+cells. Our data suggest the possibility that in IBD patients the treatment with anti-TNFαmay affect Treg percentages and that Treg modifications may correlate with clinical response, but differently in early versus late disease.

scholarly journals Interaction of measles virus glycoproteins with the surface of uninfected peripheral blood lymphocytes induces immunosuppression in vitro

1996 ◽  
Vol 93 (23) ◽  
pp. 13194-13199 ◽  
Author(s):  
J. Schlender ◽  
J.-J. Schnorr ◽  
P. Spielhofer ◽  
T. Cathomen ◽  
R. Cattaneo ◽  
...  
Keyword(s):  
Peripheral Blood ◽  
Measles Virus ◽  
Peripheral Blood Lymphocytes ◽  
Blood Lymphocytes
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